Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22951034 | 0.89 | RARB (0.48) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL18088445 | 0.89 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL22951078 | 0.86 | HDAC1 (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL17483990 | 0.84 | HDAC1 (0.52) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL17483982 | 0.83 | HDAC1 (0.59) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL18088443 | 0.77 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL17483930 | 0.76 | HDAC1 (0.54) | HDAC1HDAC2HDAC3 | |
| SCHEMBL17483925 | 0.75 | HDAC1 (0.50) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL17483983 | 0.74 | HDAC1 (0.54) | HDAC1HDAC2HDAC3HDAC6HDAC5 | |
| SCHEMBL19682890 | 0.73 | HDAC1 (0.57) | HDAC1HDAC2HDAC3HDAC6HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | THE GENERAL HOSPITAL CORPORATION | 2021-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210030899-A1 | IMAGING HISTONE DEACETYLASES WITH A RADIOTRACER USING POSITRON EMISSION TOMOGRAPHY | HDAC1, HDAC11, HDAC3 | HDAC1 1/4885HDAC2 4/4885HDAC3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.