Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952990 | 0.89 | DRD1 (0.69) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952910 | 0.87 | DRD1 (0.70) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952909 | 0.87 | DRD1 (0.67) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952912 | 0.87 | DRD1 (0.67) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952962 | 0.87 | DRD1 (0.67) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952945 | 0.84 | DRD1 (0.63) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22952950 | 0.83 | DRD1 (0.77) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL22965446 | 0.82 | DRD1 (0.77) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL21244091 | 0.82 | DRD1 (0.77) | DRD1KDM4ETP53CYP1A2CYP3A4 | |
| SCHEMBL10380340 | 0.81 | DRD1 (1.00) | DRD1KDM4ETP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |