Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 17/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952913 | 0.94 | DRD1 (0.84) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL10380336 | 0.88 | DRD1 (1.00) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL7447221 | 0.88 | DRD1 (1.00) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL9038117 | 0.88 | DRD1 (1.00) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL10380050 | 0.88 | DRD1 (1.00) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL7317977 | 0.86 | DRD1 (0.97) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL22952958 | 0.86 | DRD1 (0.79) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL8728268 | 0.86 | DRD1 (0.97) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| Hydrochloric Acid SCHEMBL7306224 | 0.86 | DRD1 (0.97) | DRD1ADRA2AADRA2BADRA2CHTR2C | |
| SCHEMBL7002535 | 0.81 | DRD1 (0.77) | DRD1ADRA2AADRA2BADRA2CHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021021922-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROTIC PATHOLOGIES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-02-04 | — | — | WO | disclosed |