Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22955338 | 0.86 | CYP3A4 (0.55) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL20806658 | 0.85 | NPC1 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL21705381 | 0.85 | HDAC6 (0.64) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL31063780 | 0.85 | HDAC6 (0.64) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL3336441 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL34460121 | 0.84 | MEN1 (0.57) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL14587771 | 0.83 | HDAC6 (0.70) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL31063832 | 0.83 | HDAC6 (0.70) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL24075254 | 0.81 | GUSB (0.50) | KDM4EALDH1A1HPGDTP53MAPT | |
| SCHEMBL22956059 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022061-A1 | ARYL HYDROCARBON RECEPTOR ACTIVATORS | OREGON STATE UNIVERSITY (US) | 2021-02-04 | — | — | WO | disclosed |