SCHEMBL2295891

SCHEMBL2295891

CC(O)c1ccc(Cl)cc1Cl

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.63
LMNA P02545 2/20 0.63
HTT P42858 1/20 0.63
PDE2A O00408 1/20 0.58
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ADRA2C P18825 1/20 0.42
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
KCNH2 Q12809 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TOP2A P11388 1/20 0.40
TOP2B Q02880 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30398975 1.00 TP53 (0.63) TP53LMNAHTTPDE2AMEN1
SCHEMBL13866426 1.00 TP53 (0.63) TP53LMNAHTTPDE2AMEN1
SCHEMBL14992635 1.00 TP53 (0.63) TP53LMNAHTTPDE2AMEN1
SCHEMBL30869925 1.00 TP53 (0.63) TP53LMNAHTTPDE2AMEN1
SCHEMBL253677 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1
SCHEMBL252437 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1
SCHEMBL29528234 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1
SCHEMBL29529206 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1
SCHEMBL29528410 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1
SCHEMBL247766 0.83 TP53 (0.59) TP53LMNAHTTPDE2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120009438-A Detection method of novel disinfection byproducts in aquatic products 舟山市食品药品检验检测研究院 2025-05-16 CN claimed
CN-109180418-B Method for synthesizing pesticide intermediate 2, 4-dichloroacetophenone by recycling propylene oxide co-product materials 江苏扬农化工集团有限公司 2021-03-30 CN claimed
CN-109180418-A A kind of propylene oxide co-production object resource utilization synthetic pesticide intermediate 2,4 dichloro benzene ethyl ketone method 江苏扬农化工集团有限公司 2019-01-11 CN claimed
CN-120192324-A Heterocyclic compound, pharmaceutical composition and application 上海医药集团股份有限公司 2025-06-24 CN disclosed
CN-120009438-A Detection method of novel disinfection byproducts in aquatic products 舟山市食品药品检验检测研究院 2025-05-16 CN disclosed
WO-2025056065-A1 CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE 上海医药集团股份有限公司 2025-03-20 WO disclosed
CN-119638669-A Chemokine receptor antagonist, pharmaceutical composition and application 上海医药集团股份有限公司 2025-03-18 CN disclosed
US-20240199620-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF RAPT THERAPEUTICS, INC. 2024-06-20 US disclosed
CN-117777000-A Synthesis method of (R) -1- (2, 4-dichlorophenyl) ethylamine and key intermediate 苏州楚凯药业有限公司 2024-03-29 CN disclosed
CN-109789146-B Chemokine receptor modulators and uses thereof 拉普特医疗公司 2023-04-18 CN disclosed
CN-115028586-A Preparation method of chiral (S) -imazalil 池州中瑞化工有限公司 2022-09-09 CN disclosed
US-5696299-A Optical resolution for producing optically active alcohol THE NISSHIN OIL MILLS, LTD. (JP) 1997-12-09 US disclosed
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5600027-A Process for producing optically active alcohol containing phenyl group THE NISSHIN OIL MILLS, LTD. (JP) 1997-02-04 US disclosed
EP-0714984-A2 Process for producing optically active alcohol containing phenyl group The Nisshin Oil Mills, Ltd. (JP) 1996-06-05 EP disclosed
EP-0709465-A2 Optical resolution for producing optically active alcohol The Nisshin Oil Mills, Ltd. (JP) 1996-05-01 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
EP-0258391-A1 USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD RHONE POULENC NEDERLAND B.V. (NL) 1988-03-09 EP disclosed
WO-1987004321-A2 USE OF HETEROCYCLIC NITROGEN-CONTAINING COMPOUNDS FOR REDUCING MOISTURE LOSS FROM PLANTS AND INCREASING CROP YIELD RHONE-POULENC NEDERLANDS B.V. (NL) 1987-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199620-A1 CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF CCR4, CCR1, CCR3 TP53 3886/4885LMNA 4831/4885HTT 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.