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SCHEMBL2295995

SCHEMBL2295995

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.49
▸ MAPK1 P28482 2/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ LMNA P02545 2/20 0.49
▸ TDP1 Q9NUW8 2/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ GAA P10253 1/20 0.48
▸ HTT P42858 1/20 0.46
▸ KDM4E B2RXH2 3/20 0.45
▸ DNM1 Q05193 1/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ EGFR P00533 1/20 0.40
▸ ADRB2 P07550 2/20 0.39
▸ ADRB1 P08588 1/20 0.39
▸ ADRB3 P13945 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10374108 1.00 MAPT (0.49) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL10675230 0.98 MAPT (0.50) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL6287761 0.83 KDM4E (0.44) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL11310011 0.81 KMT2A (0.41) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL11733434 0.81 FNTA (0.49) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL10681604 0.80 MAPT (0.51) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL10375483 0.80 MAPT (0.51) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL10678167 0.79 MAPT (0.55) MAPTMAPK1SMN1; SMN2TDP1MEN1
SCHEMBL22323471 0.78 MAPT (0.49) MAPTMAPK1SMN1; SMN2LMNATDP1
SCHEMBL1298434 0.78 MAPT (0.61) MAPTSMN1; SMN2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011083291-A1 COMBINATIONS COMPRISING AN ANT I -INFLAMMATORY AGENT AND/OR AN ANTIBACTERIAL AGENT AND A GLYCOSYLAMINE AND THEIR USE IN MEDICINE GALVEZ JULIAN MANUEL (AR) 2011-07-14 — — WO claimed
US-20010019837-A1 PROCESS FOR MICROBIALLY OXIDIZING N-SUBSTITUTED GLUCAMINES GRABNER ROY WALTER (US) 2001-09-06 — — US claimed
US-5916784-A Process for microbially oxidizing N-substituted glucamines G.D. SEARLE & COMPANY (US) 1999-06-29 — — US claimed
US-5610039-A OXIDIZING A GLUCAMINE TO PRODUCE AN INTERMEDIATE COMPOUND AND REDUCING INTERMEDIATE G. D. SEARLE & CO. (US) 1997-03-11 — — US claimed
US-5602013-A Process for producing N-substituted-1-deoxynojirimycin G. D. SEARLE & CO. (US) 1997-02-11 — — US claimed
EP-0477160-B1 Process for producing N-substituted-1-deoxynojirimycin MONSANTO CO (US) 1996-04-24 — — EP claimed
EP-0477160-A1 Process for producing N-substituted-1-deoxynojirimycin MONSANTO COMPANY (US) 1992-03-25 — — EP claimed
EP-3921067-A1 LIGAND-MODIFIED FILTER AND METHODS FOR REDUCING METALS FROM LIQUID COMPOSITIONS Entegris, Inc. (US) 2021-12-15 — — EP disclosed
WO-2020163181-A1 LIGAND-MODIFIED FILTER AND METHODS FOR REDUCING METALS FROM LIQUID COMPOSITIONS ENTEGRIS, INC. (US) 2020-08-13 — — WO disclosed
WO-2011083291-A1 COMBINATIONS COMPRISING AN ANT I -INFLAMMATORY AGENT AND/OR AN ANTIBACTERIAL AGENT AND A GLYCOSYLAMINE AND THEIR USE IN MEDICINE GALVEZ JULIAN MANUEL (AR) 2011-07-14 — — WO disclosed
US-4762933-A 1-Oxa-2-oxo-3-r-3-aza-5-z-cyclopentane derivatives BOKEL HEINZ HERMANN (DE) 1988-08-09 — — US disclosed
US-4569936-A Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones SCHERING CORPORATION (US) 1986-02-11 — — US disclosed