Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952765 | 1.00 | SCN4A (0.42) | SCN4AKMT2ASMN1; SMN2DRD1TACR1 | |
| Hydrochloric Acid SCHEMBL28711049 | 0.98 | SCN4A (0.41) | SCN4AKMT2ASMN1; SMN2DRD1TACR1 | |
| Hydrochloric Acid SCHEMBL28711046 | 0.98 | SCN4A (0.41) | SCN4AKMT2ASMN1; SMN2DRD1TACR1 | |
| SCHEMBL21272639 | 0.86 | TACR1 (0.41) | SCN4ATACR1 | |
| SCHEMBL29440424 | 0.86 | TACR1 (0.41) | SCN4ATACR1 | |
| SCHEMBL21272641 | 0.86 | TACR1 (0.41) | SCN4ATACR1 | |
| SCHEMBL22952800 | 0.86 | KMT2A (0.39) | SCN4AKMT2ASMN1; SMN2DRD1MEP1B | |
| SCHEMBL22965315 | 0.83 | SCN4A (0.39) | SCN4AKMT2ASMN1; SMN2DRD1TACR1 | |
| SCHEMBL22952697 | 0.83 | SCN4A (0.39) | SCN4AKMT2ASMN1; SMN2DRD1TACR1 | |
| SCHEMBL22952702 | 0.82 | KMT2A (0.40) | SCN4AKMT2ASMN1; SMN2DRD1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023617-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. LUNDBECK A/S (DK) | 2021-02-11 | — | — | WO | disclosed |