SCHEMBL22966264

SCHEMBL22966264

Cc1c(N=C=O)cccc1-c1ccc(C(C)(C)c2ccc(-c3cccc(N=C=O)c3C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
TRPA1 O75762 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22966408 0.94 CYP3A4 (0.50) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL25873159 0.87 CYP3A4 (0.42) CYP3A4ALDH1A1HPGDTDP1
SCHEMBL22966421 0.86 CYP3A4 (0.43) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL11352878 0.83 CYP3A4 (0.61) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL22966275 0.81 CYP3A4 (0.39) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL11334927 0.75 CYP3A4 (0.70) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL25873157 0.74 CYP3A4 (0.31) CYP3A4
SCHEMBL15092 0.74 CYP3A4 (1.00) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL27946613 0.72 CYP3A4 (0.95) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL7585382 0.70 CYP3A4 (0.52) CYP3A4ALDH1A1HPGDTDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed
US-20210038474-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INCORPORATED 2021-02-11 US disclosed