Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296669 | 1.00 | FASN (0.79) | FASN | |
| SCHEMBL2356541 | 0.91 | FASN (0.68) | FASN | |
| SCHEMBL2358746 | 0.91 | FASN (0.83) | FASN | |
| SCHEMBL2357573 | 0.90 | FASN (0.81) | FASN | |
| SCHEMBL2296370 | 0.90 | FASN (0.74) | FASN | |
| SCHEMBL2296365 | 0.90 | FASN (0.74) | FASN | |
| SCHEMBL2355630 | 0.89 | FASN (0.81) | FASN | |
| SCHEMBL12425223 | 0.89 | FASN (0.80) | FASN | |
| SCHEMBL2355745 | 0.89 | FASN (0.80) | FASN | |
| SCHEMBL2355905 | 0.89 | FASN (1.00) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2538787-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |