SCHEMBL2296943

SCHEMBL2296943

CCCc1cc(-c2ccccc2)ccn1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SREBF2 Q12772 13/20 0.64
KDM4E B2RXH2 3/20 0.49
LMNA P02545 3/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
MAPT P10636 3/20 0.47
ATM Q13315 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2D6 P10635 1/20 0.46
PSEN1 P49768 1/20 0.46
PSEN2 P49810 1/20 0.46
APH1B Q8WW43 1/20 0.46
NCSTN Q92542 1/20 0.46
APH1A Q96BI3 1/20 0.46
PSENEN Q9NZ42 1/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25500863 0.88 SREBF2 (0.52) SREBF2
SCHEMBL28684192 0.87 SREBF2 (0.50) SREBF2KDM4ELMNACYP3A4TSHR
SCHEMBL31345539 0.86 SREBF2 (0.51) SREBF2
SCHEMBL27692764 0.86 SREBF2 (0.51) SREBF2
Bromide SCHEMBL28704512 0.85 MAPT (0.50) SREBF2KDM4ELMNACYP3A4TSHR
SCHEMBL8257156 0.85 SREBF2 (0.48) SREBF2CYP3A4CYP2D6PSEN1PSEN2
SCHEMBL4283881 0.79 SREBF2 (1.00) SREBF2KDM4ELMNAMAPTATM
SCHEMBL15104622 0.78 SIRT2 (0.45) SREBF2L3MBTL1ALDH1A1
SCHEMBL19758238 0.78 SREBF2 (0.50) SREBF2KDM4ELMNACYP3A4TSHR
Hydrochloric Acid SCHEMBL8351731 0.77 HRH1 (0.49) SREBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO claimed
CN-101547985-B Method for manufacturing flexible laminate ASHLAND LICENSING & INTELLECTU 2014-02-26 CN claimed
CN-101547985-A Method for manufacturing flexible laminate ASHLAND INC (US) 2009-09-30 CN claimed
CN-1181093-A Chemical binder MANCUSO CHEMICALS LTD (CA) 1998-05-06 CN claimed
US-5698613-A Chemical binder MANCUSO CHEMICALS LIMITED (CA) 1997-12-16 US claimed
US-4615372-A BLEND OF METAL DRIER TO PHENOLIC URETHANE BINDER DELTA RESINS & REFRACTORIES (US) 1986-10-07 US claimed
US-4568728-A ACID SETTING PHENOLIC RESIN WITH ZIRCONIUM DRIER DELTA RESINS & REFRACTORIES (US) 1986-02-04 US claimed
US-4311631-A Low emission foundry binder system DELTA OIL PRODUCTS CORPORATION (US) 1982-01-19 US claimed
US-4148777-A THERMOSETTING POLYURETHANES DELTA OIL PRODUCTS CORPORATION (US) 1979-04-10 US claimed
US-4079031-A PHENOLIC RESIN, POLYETHER POLYOL, POLYISOCYANATE DELTA OIL PRODUCTS CORPORATION (US) 1978-03-14 US claimed
JP-62259636-A None JP disclosed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US disclosed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP disclosed
US-20240033809-A1 SMOKE-SUPPRESSING ADDITIVE FOR POLYURETHANE-FORMING BINDER SYSTEM ASK Chemicals LLC 2024-02-01 US disclosed
US-4144215-A CURING, AGGREGATES, FOR CASTINGS INTERNATIONAL MINERALS & CHEMICAL CORP. (US) 1979-03-13 US disclosed
US-4124556-A Moulding composition containing (a) silane additive (b) iron oxide and (c) polyurethane resin and method for preparing shaped foundry products ASHLAND OIL, INC. (US) 1978-11-07 US disclosed
US-4079031-A PHENOLIC RESIN, POLYETHER POLYOL, POLYISOCYANATE DELTA OIL PRODUCTS CORPORATION (US) 1978-03-14 US disclosed
US-3948824-A Cellular polymeric masses ASHLAND OIL, INC. (US) 1976-04-06 US disclosed