Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23181274 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL23180190 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL23690558 | 0.95 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL23181275 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL25100621 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL25100480 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL15146938 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL14870351 | 0.87 | HTT (0.46) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL25100617 | 0.87 | HPGD (0.40) | SMN1; SMN2HPGDHTTTP53HDAC3 | |
| SCHEMBL20647310 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTTP53HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022678-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-02-11 | — | — | WO | disclosed |