Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602752 | 0.95 | TSHR (0.35) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10129066 | 0.92 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26614403 | 0.92 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26754913 | 0.92 | — | — | |
| SCHEMBL22722883 | 0.87 | TSHR (0.38) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12717161 | 0.86 | TSHR (0.36) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24837667 | 0.84 | TSHR (0.39) | TSHRSLC6A2SLC6A4SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL28870908 | 0.84 | TSHR (0.35) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18159150 | 0.81 | HTT (0.42) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29120904 | 0.81 | TSHR (0.33) | TSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023247-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | WO | disclosed |