⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723804 | 0.66 | — | — | |
| SCHEMBL20643591 | 0.59 | — | — | |
| SCHEMBL3045315 | 0.58 | — | — | |
| SCHEMBL3176034 | 0.55 | — | — | |
| SCHEMBL6033539 | 0.55 | — | — | |
| SCHEMBL404105 | 0.55 | — | — | |
| SCHEMBL1938866 | 0.55 | — | — | |
| SCHEMBL2930698 | 0.55 | — | — | |
| SCHEMBL6154815 | 0.55 | — | — | |
| SCHEMBL8909857 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11439612-B2 | Formulations for administration of eflornithine | Orbus Therapeutics, Inc. (US) | 2022-09-13 | — | — | US | disclosed |
| US-20210038549-A1 | FORMULATIONS FOR ADMINISTRATION OF EFLORNITHINE | Orbus Therapeutics, Inc. | 2021-02-11 | — | — | US | disclosed |