SCHEMBL22970547

SCHEMBL22970547

C1=CC(c2ccccc2)Nc2c1ccc1ccc(-c3ccc(-c4ccc5ccc(-c6ccc7ccc(-c8ccccn8)nc7c6)nc5c4)cc3)nc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.31
IGF1R P08069 2/20 0.31
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22970179 0.85 KDM4E (0.34) IGF1RCYP3A4
SCHEMBL22970424 0.83 IGF1R (0.32) IGF1RCYP3A4
SCHEMBL22970207 0.82
SCHEMBL23954437 0.80 PARP1 (0.37)
SCHEMBL19768553 0.80 CCR1 (0.36)
SCHEMBL22111564 0.79 PARP1 (0.36)
SCHEMBL22970292 0.79 IGF1R (0.31) IGF1RCYP3A4
SCHEMBL22970524 0.79 IGF1R (0.41) DHODHIGF1RCYP3A4
SCHEMBL22970166 0.78 TOP1 (0.42) DHODHIGF1RCYP3A4
SCHEMBL21616033 0.78 PARP1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021025356-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME 엘티소재주식회사 2021-02-11 WO disclosed