Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 16/20 | 0.45 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18038386 | 0.86 | IL2 (0.45) | IL2 | |
| SCHEMBL25976758 | 0.86 | IL2 (0.54) | IL2STIM1ORAI1NPC1CYP1A2 | |
| SCHEMBL18038387 | 0.82 | STIM1 (0.55) | IL2STIM1ORAI1ORAI2GCK | |
| SCHEMBL30096509 | 0.82 | STIM1 (0.55) | IL2STIM1ORAI1ORAI2GCK | |
| SCHEMBL12155849 | 0.73 | IL2 (0.58) | IL2STIM1ORAI1ORAI2 | |
| SCHEMBL12155920 | 0.71 | IL2 (0.48) | IL2NPC1RAB9A | |
| SCHEMBL1701936 | 0.71 | IL2 (0.58) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL12155915 | 0.71 | IL2 (0.58) | IL2STIM1ORAI1ORAI2NPC1 | |
| SCHEMBL12156314 | 0.71 | IL2 (0.55) | IL2STIM1ORAI1ORAI2 | |
| SCHEMBL12155919 | 0.71 | IL2 (0.58) | IL2STIM1ORAI1ORAI2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778595-A1 | PANCREATITIS TREATMENT | Calcimedica, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |