Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21248721 | 1.00 | EGFR (0.42) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL22975141 | 0.93 | CHRM2 (0.38) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL21264259 | 0.93 | CHRM2 (0.38) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL21264263 | 0.92 | CHRM2 (0.38) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL21248086 | 0.87 | MAPT (0.38) | EGFRALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL21248087 | 0.87 | MAPT (0.38) | EGFRALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL21264232 | 0.83 | EGFR (0.36) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL21264234 | 0.83 | EGFR (0.36) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL23010135 | 0.83 | MAPT (0.35) | EGFRDNM1ALDH1A1KMT2ALMNA | |
| SCHEMBL21264171 | 0.83 | MAPT (0.41) | ALDH1A1KMT2ALMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168077-B2 | Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168077-B2 | Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-11-09 | — | — | US | disclosed |
| US-20210047308-A1 | MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-20210047308-A1 | MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168077-B2 | Molecular rotor-based D-amino acids as tools for imaging peptidoglycan biosynthesis | DDOST, DAD1, DAO | EGFR 2179/4885DNM1 1252/4885ALDH1A1 4654/4885 |
| US-20210047308-A1 | MOLECULAR ROTOR-BASED D-AMINO ACIDS AS TOOLS FOR IMAGING PEPTIDOGLYCAN BIOSYNTHESIS | DDOST, DAD1, DAO | EGFR 2179/4885DNM1 1252/4885ALDH1A1 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.