SCHEMBL22975418

SCHEMBL22975418

COC[C@@H](OC[C@H]1O[C@@H](n2ncc3c(NC4CCCC4)nc(Cl)nc32)[C@H](O)[C@@H]1O)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NT5E P21589 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22975774 1.00 NT5E (1.00) NT5E
SCHEMBL22975421 1.00 NT5E (1.00) NT5E
SCHEMBL24618911 1.00 NT5E (1.00) NT5E
SCHEMBL23007171 0.93 NT5E (0.87) NT5E
SCHEMBL22975569 0.92 NT5E (0.87) NT5E
SCHEMBL23006800 0.92 NT5E (0.85) NT5E
SCHEMBL24619066 0.92 NT5E (0.85) NT5E
SCHEMBL29616126 0.92 NT5E (0.85) NT5E
SCHEMBL24618905 0.91 NT5E (1.00) NT5E
SCHEMBL22975445 0.91 NT5E (1.00) NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674481-A2 CD73 INHIBITORS Oric Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
US-20250368677-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2025-12-04 US disclosed
EP-3787635-B1 CD73 INHIBITORS ORIC PHARMACEUTICALS INC (US) 2025-09-17 EP disclosed
US-20240124512-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2024-04-18 US disclosed
US-11807658-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
US-11807658-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
US-11807658-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2023-11-07 US disclosed
US-20220220147-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2022-07-14 US disclosed
US-20220220147-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2022-07-14 US disclosed
US-11325938-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2022-05-10 US disclosed
US-11325938-B2 CD73 inhibitors ORIC PHARMACEUTICALS, INC. (US) 2022-05-10 US disclosed
US-20210047359-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2021-02-18 US disclosed
US-20210047359-A1 CD73 INHIBITORS ORIC PHARMACEUTICALS, INC. 2021-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124512-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-11807658-B2 CD73 inhibitors ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20220220147-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-11325938-B2 CD73 inhibitors ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20250368677-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885
US-20210047359-A1 CD73 INHIBITORS ENTPD5, NT5E, ENTPD1 NT5E 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.