⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4237662 | 0.65 | — | — | |
| SCHEMBL7433734 | 0.65 | — | — | |
| SCHEMBL11600094 | 0.51 | — | — | |
| SCHEMBL186926 | 0.50 | — | — | |
| SCHEMBL4362773 | 0.50 | — | — | |
| SCHEMBL10409928 | 0.49 | — | — | |
| SCHEMBL5690944 | 0.49 | — | — | |
| SCHEMBL1222047 | 0.49 | — | — | |
| SCHEMBL38659478 | 0.47 | — | — | |
| SCHEMBL277574 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-B1 | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of Protein Jun-kinases | MERCK SERONO SA (CH) | 2013-09-04 | — | — | EP | claimed |
| US-8008341-B2 | Central nervous system disorders; autoimmune diseases; anticancer agents; cardiovascular disorders; antiischemic agents; antiepileptic agents ; Alzheimer's disease; Huntington's disease; Parkinson's disease; spinal cord injuries; antiarthritic agents; transplant rejection; sepsis; brain disorders | MERCK SERONO SA (CH) | 2011-08-30 | — | — | US | claimed |
| EP-1320526-B1 | PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES | MERCK SERONO SA (CH) | 2010-08-18 | — | — | EP | claimed |
| US-7544700-B2 | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein JunKinases | LABORATOIRES SERONO SA (CH) | 2009-06-09 | — | — | US | claimed |
| US-20080255222-A1 | PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2008-10-16 | — | — | US | claimed |
| US-7417058-B2 | Pharmaceutically active benzsulfonamide derivatives as inhibitors of protein junkinases | LABORATOIRES SERONO S.A. (CH) | 2008-08-26 | — | — | US | claimed |
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |
| US-20040077854-A1 | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moietties as inhibitors of protein junkinases | MERCK SERONO SA (CH) | 2004-04-22 | — | — | US | claimed |
| US-20040053917-A1 | Pharmaceutically active benzsulfonamide derivatives as inhibitors of protein junkinases | MERCK SERONO SA (CH) | 2004-03-18 | — | — | US | claimed |
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| EP-1320526-A1 | PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-06-25 | — | — | EP | claimed |
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |
| WO-2002026711-A1 | PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |
| EP-1193256-A1 | Pharmaceutically active benzsulfonamide derivatives as inhibitors of JNK proteins | Applied Research Systems ARS Holding N.V. (AN) | 2002-04-03 | — | — | EP | claimed |
| EP-1193268-A1 | Pharmaceutically active sulfonamide derivatives bearing both lipophilic and ionisable moieties as inhibitors of protein Junkinases | Applied Research Systems ARS Holding N.V. (AN) | 2002-04-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |
| CN-111615388-B | Immunotherapeutic agent for cancer | 斯汀格瑞治疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |
| EP-0393711-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |