Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988844 | 0.89 | CSF1R (0.59) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22978448 | 0.85 | CSF1R (0.55) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22978456 | 0.83 | CSF1R (0.56) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22988858 | 0.83 | CSF1R (0.58) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22988850 | 0.83 | CSF1R (0.58) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22978446 | 0.80 | CSF1R (0.56) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22988857 | 0.75 | CSF1R (0.49) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22988845 | 0.75 | CSF1R (0.49) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22988859 | 0.74 | CSF1R (0.47) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL22978460 | 0.72 | CSF1R (0.60) | CSF1RCYP3A4MTNR1AMTNR1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018233526-A9 | CSF1R INHIBITOR, AND MANUFACTURING METHOD THEREFOR AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |
| CN-110461849-B | CSF1R inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2020-09-01 | — | — | CN | disclosed |
| CN-110461849-A | A kind of CSF1R inhibitor and its preparation method and application | ABBISKO THERAPEUTICS CO LTD | 2019-11-15 | — | — | CN | disclosed |