Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 6/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427744 | 0.83 | DDB1 (0.48) | RBP4NPC1MAPTRAB9A | |
| SCHEMBL23980883 | 0.78 | DDB1 (0.47) | RBP4NPC1MAPTRAB9A | |
| SCHEMBL14862849 | 0.78 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21340182 | 0.77 | CD44 (0.56) | HTR2CCD44HTR2BHTR2AHTR6 | |
| Hydrochloric Acid SCHEMBL21326076 | 0.75 | CD44 (0.54) | HTR2CCD44HTR2BHTR6 | |
| Hydrochloric Acid SCHEMBL29588004 | 0.75 | CD44 (0.54) | HTR2CCD44HTR2BHTR6 | |
| SCHEMBL25426004 | 0.74 | DDB1 (0.48) | RBP4NPC1MAPTRAB9A | |
| SCHEMBL14863721 | 0.73 | TAAR1 (0.45) | HTR2CCD44HTR2BHTR2A | |
| SCHEMBL20140665 | 0.70 | PROKR1 (0.50) | RBP4ALDH1A1POLBNPC1MAPT | |
| SCHEMBL27840577 | 0.69 | CD44 (0.44) | HTR2CCD44HTR2BHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2021026672-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | NOVARTIS AG (CH) | 2021-02-18 | — | — | WO | disclosed |