Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22981147 | 1.00 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29646458 | 1.00 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29645938 | 1.00 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL22979373 | 1.00 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29645531 | 1.00 | CYP1A2 (0.41) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL22979391 | 0.90 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL22979228 | 0.90 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL22979468 | 0.90 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29645753 | 0.90 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR | |
| SCHEMBL29646184 | 0.90 | CYP1A2 (0.43) | CYP1A2HSD17B10CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | claimed |