Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590923 | 0.94 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL1591230 | 0.94 | PTGER4 (0.58) | PTGER4 | |
| SCHEMBL2297543 | 0.94 | PTGER4 (0.73) | PTGER4 | |
| SCHEMBL1591529 | 0.88 | PTGER4 (0.65) | PTGER4 | |
| SCHEMBL1591299 | 0.88 | PTGER4 (0.65) | PTGER4 | |
| SCHEMBL2296581 | 0.87 | PTGER4 (0.61) | PTGER4 | |
| SCHEMBL3569685 | 0.85 | PTGER4 (0.71) | PTGER4 | |
| SCHEMBL2299789 | 0.85 | PTGER4 (0.49) | PTGER4 | |
| SCHEMBL2297444 | 0.84 | PTGER4 (0.85) | PTGER4 | |
| SCHEMBL1590463 | 0.84 | PTGER4 (0.57) | PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201663-A1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201663-A1 | BENZO (F) ISOINDOL-2-YLPHENYL ACETIC ACID DERIVATIVES AS EP4 RECEPTOR AGONISTS | PTGER4, PTGER1, PTGER2 | PTGER4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.