Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | GAPDH | P04406 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256521 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL7943170 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL9002154 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL22992612 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL9221115 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL23906728 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL19326815 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL10459898 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL22992319 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL2027546 | 1.00 | MEN1 (0.71) | MEN1USP2POLBKMT2AGAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |