SCHEMBL22984085

SCHEMBL22984085

CCNC(=O)c1ccc(CNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.59
HTT P42858 2/20 0.51
USP2 O75604 1/20 0.50
LMNA P02545 2/20 0.49
TSHR P16473 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
MEN1 O00255 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ALDH1A1 P00352 1/20 0.48
MDM2 Q00987 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29300517 0.87 FOLH1 (0.65) FOLH1HDAC3HDAC1HDAC6
SCHEMBL22106236 0.85 HDAC1 (0.56) TSHRSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL18811751 0.85 HDAC1 (0.56) TSHRSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL16297725 0.85 HTT (0.57) HTTUSP2LMNAKMT2AGAA
SCHEMBL18659987 0.84 CA1 (0.60) HTTUSP2LMNAKMT2AGAA
SCHEMBL10284232 0.83 GAA (0.55) FOLH1HTTUSP2LMNATSHR
SCHEMBL29299810 0.82 FOLH1 (0.70) FOLH1HTTLMNATSHRKMT2A
SCHEMBL23504877 0.80 FOLH1 (0.68) FOLH1TSHRKMT2AMEN1HDAC3
SCHEMBL24115204 0.80 FOLH1 (0.62) FOLH1TSHRKMT2AMEN1HDAC3
SCHEMBL23504874 0.77 FOLH1 (0.67) FOLH1HDAC3HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919938-B2 Modified cyclopentapeptides and uses thereof Technische Universität München (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919938-B2 Modified cyclopentapeptides and uses thereof ANXA4, CPA4, PTMS FOLH1 259/4885HTT 945/4885USP2 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.