Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5470982 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL16198513 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL29662193 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL29662238 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL29662201 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL16198555 | 0.83 | HTR2A (0.50) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL28779678 | 0.81 | HTR2A (0.49) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL29662293 | 0.81 | HTR2A (0.49) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL28779675 | 0.81 | HTR2A (0.49) | SMN1; SMN2EPHX2TBXAS1ADRB1ADRB2 | |
| SCHEMBL2577931 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2EPHX2CYP17A1TBXAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10918687-B2 | Kava derived therapeutic compounds and methods of use thereof | KUALITY HERBCEUTICS LLC (US) | 2021-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10918687-B2 | Kava derived therapeutic compounds and methods of use thereof | KLK5, KLK4, KLK2 | SMN1; SMN2 2154/4885EPHX2 2445/4885CYP17A1 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.