SCHEMBL22985159

SCHEMBL22985159

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc(-c2ccc(C#N)cc2C(F)(F)F)c(-c2cc(C#N)ccc2-n2c3ccc(C(C)(C)C)cc3c3cc(C(C)(C)C)ccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.34
TRPV4 Q9HBA0 1/20 0.34
ELANE P08246 2/20 0.32
KIF11 P52732 1/20 0.32
CSNK1D P48730 2/20 0.31
CSNK1G2 P78368 2/20 0.31
PPARG P37231 1/20 0.30
CASP3 P42574 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22985157 0.95 AR (0.33) ARTRPV4ELANEKIF11PPARG
SCHEMBL22985589 0.94 AR (0.35) ARTRPV4ELANEKIF11
SCHEMBL20848811 0.92 AR (0.33) ARTRPV4ELANEKIF11
SCHEMBL20848872 0.92 PPARG (0.34) ARELANEKIF11PPARG
SCHEMBL20849196 0.92 PPARG (0.34) ARELANEKIF11PPARG
SCHEMBL22985178 0.92 AR (0.38) ARTRPV4ELANEKIF11CASP3
SCHEMBL20848964 0.90 AR (0.33) ARTRPV4ELANEKIF11
SCHEMBL22985581 0.89 ELANE (0.34) ARELANEKIF11PPARG
SCHEMBL20849418 0.89 ELANE (0.32) ARTRPV4ELANE
SCHEMBL22985161 0.89 AR (0.35) ARTRPV4ELANECASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 AR 3541/4885TRPV4 145/4885ELANE 3847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.