Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298519 | 1.00 | FASN (0.72) | FASN | |
| SCHEMBL12425390 | 0.94 | FASN (0.70) | FASN | |
| SCHEMBL2301615 | 0.94 | FASN (0.72) | FASN | |
| SCHEMBL14152399 | 0.92 | FASN (0.60) | FASN | |
| SCHEMBL2301429 | 0.91 | FASN (0.62) | FASN | |
| SCHEMBL2301422 | 0.91 | FASN (0.62) | FASN | |
| SCHEMBL12425232 | 0.91 | FASN (0.60) | FASN | |
| SCHEMBL2298006 | 0.91 | FASN (0.61) | FASN | |
| SCHEMBL2297993 | 0.91 | FASN (0.61) | FASN | |
| SCHEMBL12425590 | 0.90 | FASN (0.76) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2538787-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |