Uric Acid

Uric Acid

SCHEMBL229866

O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1.[NaH]

nearest known ligand 0.94

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.94
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
HPGD P15428 2/20 0.46
CYP2C19 P33261 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
BRPF1 P55201 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TYMP P19971 5/20 0.39
GSK3B P49841 1/20 0.39
BACE1 P56817 1/20 0.39
IDH1 O75874 1/20 0.39
CSNK2A2 P19784 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL924097 0.97 GDA (0.89) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL3417988 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL22069923 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL7933 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1331321 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL11473111 0.95 GDA (0.84) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL2434620 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL16213309 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL196769 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1071965 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5171 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119791058-B Pain rheumatism heat syndrome subtype modeling method, biomarker group application and detection method 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2026-05-19 CN claimed
CN-118370268-B Construction method of uric acid crystallization kidney injury animal model 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2026-05-12 CN claimed
US-12566174-B2 Method and kit for determining the presence of monosodium urate crystals in joint synovial fluid THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2026-03-03 US claimed
CN-121582139-A Target symptom identification method, device, equipment and medium based on dual-energy CT 国科离子医疗科技有限公司 2026-02-27 CN claimed
US-12324799-B2 Methods and uses of colchicine derivatives ALBERTA HEALTH SERVICES (CA) 2025-06-10 US claimed
CN-119804581-A Quality control liquid and application thereof 艾康生物技术(杭州)有限公司 2025-04-11 CN claimed
CN-119791058-A Pain rheumatism heat syndrome subtype modeling method, biomarker group application and detection method 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2025-04-11 CN claimed
CN-118111933-B Equipment for evaluating gout attack risk based on monosodium urate crystal growth rate 南方医科大学南方医院 2025-04-04 CN claimed
EP-4528273-A1 QUALITY CONTROL SOLUTION AND USE THEREOF Leadway (HK) Limited (CN) 2025-03-26 EP claimed
WO-2025037010-A1 FUSED PIPERIDINYL BICYCLIC AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF DISEASES INFLARX GMBH (DE) 2025-02-20 WO claimed
US-6544726-B1 Mixture for organ preservation VAN DYKE KNOX (US) 2003-04-08 US claimed
US-20030040036-A1 Synovial fluid control QUANTIMETRIX CORPORATION 2003-02-27 US claimed
US-20020132758-A1 Method for identifying compounds to treat medical pathologies associated with molecular crystallization SHELL JOHN W (US) 2002-09-19 US claimed
WO-2002057796-A2 COMPOUNDS FOR TREATING PATHOLOGIES ASSOCIATED WITH MOLECULAR CRYSTALLIZATION SHELL JOHN W (US) 2002-07-25 WO claimed
WO-2002000933-A2 SCREENING ASSAYS FOR IDENTIFYING MODULATORS OF THE INFLAMMATORY OR IMMUNE RESPONSES INTERLEUKIN GENETICS, INC. (US) 2002-01-03 WO claimed
EP-1159941-A2 Formulations for use in enzyme-orthokeratology Ista Pharmaceuticals, Inc. (US) 2001-12-05 EP claimed
CN-1279275-A Disinfecting washing powder and its preparing process MINGFENG DAILY CHEMICALS CO LT (CN) 2001-01-10 CN claimed
CN-1258448-A Hand disinfectant for preoperation use and personal hygiene and its preparation TIANJIN AIHUA FRESHENER CO LTD (CN) 2000-07-05 CN claimed
US-5648228-A Measuring activity toward production of activated blood coagulation factor XII, plasma kallikrein or bradykinin using reconstituted kallikrein-kinin system NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1997-07-15 US claimed
US-5599683-A Method for measuring production activity of test substance towards FXIIa NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) 1997-02-04 US claimed