Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600423 | 0.96 | CA1 (0.40) | CA1CA2ALDH1A1ECE1RECQL | |
| SCHEMBL30744226 | 0.83 | ECE1 (0.50) | CA1CA2ECE1MEN1KMT2A | |
| SCHEMBL21440819 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL10005766 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL21440849 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL16945824 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL21440852 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL20887524 | 0.82 | CA1 (0.37) | CA1CA2ALDH1A1RECQL | |
| SCHEMBL18466189 | 0.82 | PAOX (0.36) | CA1CA2ALDH1A1ECE1RECQL | |
| SCHEMBL15984918 | 0.80 | CA1 (0.41) | CA1CA2ALDH1A1RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |