Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | HAVCR2 | Q8TDQ0 | 2/20 | 0.62 |
| ▸ | XDH | P47989 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | PAK4 | O96013 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987431 | 0.91 | KDM4E (0.72) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22988100 | 0.91 | KDM4E (0.78) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987493 | 0.88 | KDM4E (0.73) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987949 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987993 | 0.87 | KDM4E (0.72) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987507 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987895 | 0.84 | KDM4E (0.81) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987594 | 0.84 | KDM4E (0.68) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22987532 | 0.84 | KDM4E (0.78) | KDM4EALDH1A1POLBHAVCR2XDH | |
| SCHEMBL22979094 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1POLBHAVCR2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | KDM4E 1364/4885ALDH1A1 597/4885POLB 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.