Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197853 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| Hydrochloric Acid SCHEMBL28730339 | 0.99 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL15414033 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL4701054 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL7329154 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL16382728 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19NPC1RAB9AKMT2A | |
| SCHEMBL28084325 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL7320268 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL7433956 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AGLA | |
| SCHEMBL7356715 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP2C19NPC1RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2022029063-A1 | PYRIDO[1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-02-10 | — | — | WO | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | SMN1; SMN2 4234/4885CYP2C19 269/4885NPC1 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.