SCHEMBL22989013

SCHEMBL22989013

c1ccc(-c2ccc(-c3nc(-c4ccc(-n5c6ccc7cccc8oc9cccc%10ccc5c(c%109)c6c78)c5ccccc45)nc4c3sc3ccccc34)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
MMP14 P50281 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989007 0.95
SCHEMBL22988975 0.95 MEN1 (0.32) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL22989074 0.92 MEN1 (0.32) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL22989040 0.91 PRKDC (0.36) PRKDC
SCHEMBL22989010 0.91 PRKDC (0.34) PRKDC
SCHEMBL22989231 0.90 MEN1 (0.33) MEN1LMNAMAPTMAPK1RECQL
SCHEMBL22989139 0.89 PRKDC (0.33) PRKDC
SCHEMBL22989009 0.89 PRKDC (0.34) PRKDC
SCHEMBL22988976 0.88 PRKDC (0.30) PRKDC
SCHEMBL22989075 0.88 PRKDC (0.35) PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2016-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 JAK2, JAK3, PAK3 MEN1 4552/4885LMNA 4084/4885MAPT 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.