Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25706542 | 0.90 | EPHX1 (0.51) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13712548 | 0.90 | EPHX1 (0.51) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25913114 | 0.82 | NR1H2 (0.43) | NR1H2EPHX1NAMPTALDH1A1MAPT | |
| SCHEMBL3827461 | 0.82 | NR1H2 (0.51) | NR1H2EPHX1NAMPTALDH1A1MAPT | |
| SCHEMBL29589514 | 0.81 | EHMT2 (0.40) | NR1H2EPHX1ALDH1A1MAPTMEN1 | |
| SCHEMBL26030780 | 0.81 | NR1H2 (0.43) | NR1H2EPHX1NAMPTALDH1A1MAPT | |
| SCHEMBL24654594 | 0.81 | NR1H2 (0.50) | NR1H2EPHX1NAMPTALDH1A1MAPT | |
| SCHEMBL20267838 | 0.80 | EPHX1 (0.58) | EPHX1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20030794 | 0.80 | NR1H2 (0.47) | NR1H2EPHX1NAMPTALDH1A1MAPT | |
| SCHEMBL21081463 | 0.79 | NR1H2 (0.49) | NR1H2EPHX1NAMPTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097187-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2021027943-A1 | PYRIMIDINOPYRIDAZINONE DERIVATIVE AND MEDICAL USE THEREOF | 正大天晴药业集团南京顺欣制药有限公司 | 2021-02-18 | — | — | WO | disclosed |