Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.71 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.71 |
| ▸ | CTSD | P07339 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17815408 | 1.00 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL17815404 | 0.93 | BACE1 (0.69) | BACE1BACE2CTSD | |
| SCHEMBL11917604 | 0.92 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL11917958 | 0.90 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL17815402 | 0.90 | BACE1 (0.82) | BACE1BACE2CTSD | |
| SCHEMBL11917603 | 0.90 | BACE1 (0.82) | BACE1BACE2CTSD | |
| SCHEMBL11917950 | 0.90 | BACE1 (0.73) | BACE1BACE2CTSD | |
| SCHEMBL11917892 | 0.90 | BACE1 (0.73) | BACE1BACE2CTSD | |
| SCHEMBL14817193 | 0.89 | BACE1 (0.71) | BACE1BACE2CTSD | |
| SCHEMBL11917952 | 0.87 | BACE1 (0.75) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511268-B2 | OXAZINE DERIVATIVE | SHIONOGI & CO (JP) | 2021-02-17 | — | — | EP | disclosed |