Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 3/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620056 | 0.85 | GBA1 (0.41) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL24882683 | 0.81 | GLB1 (0.54) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL24090559 | 0.81 | GLB1 (0.54) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL13656342 | 0.80 | — | — | |
| SCHEMBL22991904 | 0.80 | GBA1 (0.67) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL23767404 | 0.80 | GUSB (0.59) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL22778679 | 0.79 | GLB1 (0.52) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL20109895 | 0.79 | GBA1 (0.39) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL17918911 | 0.76 | GLB1 (0.54) | GLB1GBA1EBPSIGMAR1GUSB | |
| SCHEMBL21276612 | 0.76 | GLB1 (0.54) | GLB1GBA1EBPSIGMAR1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030711-A1 | ALKYNYL QUINAZOLINE COMPOUNDS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |