SCHEMBL22991978

SCHEMBL22991978

CC#CCOc1cc(/C=C/n2c(C)cc(=O)cc2C)ccc1C

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22714053 0.88 PDE4B (1.00) PDE4B
SCHEMBL22714052 0.88 PDE4B (1.00) PDE4B
SCHEMBL22991946 0.87 PDE4B (0.79) PDE4B
SCHEMBL22991977 0.81 PDE4B (0.66) PDE4B
SCHEMBL22992054 0.81 PDE4B (0.78) PDE4B
SCHEMBL22991974 0.81 PDE4B (0.78) PDE4B
SCHEMBL22991991 0.81 PDE4B (0.78) PDE4B
SCHEMBL22991943 0.79 PDE4B (0.79) PDE4B
SCHEMBL110052 0.76 PDE4B (0.46) PDE4B
SCHEMBL22991947 0.76 PDE4B (0.77) PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3777979-A1 ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF Vivavision Biotech, Inc. (CN) 2021-02-17 EP disclosed