SCHEMBL22993117

SCHEMBL22993117

Fc1ccc(-c2ccc3c(-c4ccc5ccccc5c4)c4ccccc4c(-c4ccc(OC(F)(F)F)cc4)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.39
KIF11 P52732 1/20 0.38
SERPINE1 P05121 2/20 0.38
SCN5A Q14524 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
MMP3 P08254 1/20 0.36
CYP1A2 P05177 4/20 0.36
CYP2A6 P11509 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
AURKA O14965 1/20 0.35
TPX2 Q9ULW0 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
MTOR P42345 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993206 1.00 ACP1 (0.39) ACP1KIF11SERPINE1SCN5APTGDR2
SCHEMBL22993533 0.95 ACP1 (0.41) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22993279 0.94 ACP1 (0.42) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22993064 0.92 ACP1 (0.43) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22992915 0.90 SERPINE1 (0.39) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22993519 0.89 ESR1 (0.39) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22993100 0.89 ACP1 (0.40) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22992902 0.89 ACP1 (0.40) ACP1KIF11SERPINE1SCN5AMMP3
SCHEMBL22993521 0.88 CYP1A2 (0.46) CYP1A2CYP2A6ESR1ESR2PIK3CD
SCHEMBL13006999 0.88 CYP1A2 (0.46) CYP1A2CYP2A6ESR1ESR2PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed