SCHEMBL22993261

SCHEMBL22993261

Cc1cc2c(-c3ccc(OC(F)(F)F)cc3)c3cc(C)c(C)cc3c(-c3ccc4ccccc4c3)c2cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.42
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
SCN5A Q14524 2/20 0.38
PTGDR2 Q9Y5Y4 2/20 0.38
IKBKB O14920 1/20 0.38
KIF11 P52732 2/20 0.36
AURKA O14965 1/20 0.36
TPX2 Q9ULW0 1/20 0.36
HSD11B1 P28845 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.36
BCL2L1 Q07817 1/20 0.36
AR P10275 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21224360 0.88 ACP1 (0.46) ACP1SCN5AKIF11AURKATPX2
SCHEMBL22993011 0.87 ACP1 (0.40) ACP1SCN5APTGDR2KIF11AURKA
SCHEMBL22993533 0.84 ACP1 (0.41) ACP1SCN5AKIF11AURKATPX2
SCHEMBL22992902 0.84 ACP1 (0.40) ACP1SCN5AKIF11AURKATPX2
SCHEMBL22993100 0.84 ACP1 (0.40) ACP1SCN5AKIF11AURKATPX2
SCHEMBL22993279 0.83 ACP1 (0.42) ACP1SCN5AKIF11AURKATPX2
SCHEMBL22993157 0.83 PPARG (0.44) ACP1KDM4EGAAMAPTMAPK1
SCHEMBL260950 0.83 IKBKB (0.49) IKBKBCYP11B1CYP11B2CYP1A2CYP2A6
SCHEMBL29416662 0.83 IKBKB (0.49) IKBKBCYP11B1CYP11B2CYP1A2CYP2A6
SCHEMBL22993032 0.82 ESR1 (0.43) ACP1MAPTIKBKBKIF11HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed