Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637387 | 0.72 | HTR2A (0.43) | HTR2ACHRM2CHRM1 | |
| SCHEMBL25019995 | 0.64 | — | — | |
| SCHEMBL20974658 | 0.63 | HTR2C (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19637169 | 0.63 | TDP1 (0.33) | TDP1 | |
| SCHEMBL22360876 | 0.59 | HTT (0.36) | — | |
| SCHEMBL21003236 | 0.58 | CHRM3 (0.49) | HTR2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25324693 | 0.58 | HTR2C (0.38) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19170288 | 0.55 | SLC29A1 (0.38) | — | |
| SCHEMBL632364 | 0.55 | PDE10A (0.39) | — | |
| SCHEMBL12384254 | 0.54 | LOX (0.42) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458445-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2021-02-17 | — | — | EP | disclosed |