Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19636799 | 0.96 | KRAS (0.76) | KRAS | |
| SCHEMBL19637144 | 0.92 | KRAS (0.76) | KRAS | |
| SCHEMBL19637053 | 0.92 | KRAS (0.75) | KRAS | |
| SCHEMBL19636791 | 0.91 | KRAS (0.79) | KRAS | |
| SCHEMBL19617301 | 0.90 | KRAS (0.73) | KRAS | |
| SCHEMBL19637121 | 0.90 | KRAS (0.78) | KRAS | |
| SCHEMBL30189043 | 0.90 | KRAS (0.78) | KRAS | |
| SCHEMBL19637200 | 0.89 | KRAS (0.78) | KRAS | |
| SCHEMBL19637065 | 0.88 | KRAS (0.75) | KRAS | |
| SCHEMBL19617214 | 0.88 | KRAS (0.75) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458445-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2021-02-17 | — | — | EP | disclosed |