Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17385147 | 0.88 | EGFR (0.76) | EGFR | |
| SCHEMBL29423851 | 0.88 | EGFR (0.76) | EGFR | |
| SCHEMBL17384850 | 0.88 | EGFR (0.76) | EGFR | |
| SCHEMBL17385146 | 0.88 | EGFR (0.76) | EGFR | |
| SCHEMBL19103313 | 0.88 | EGFR (0.55) | EGFR | |
| SCHEMBL17384788 | 0.86 | EGFR (0.62) | EGFRKCNH2IGF1R | |
| SCHEMBL22994862 | 0.86 | EGFR (0.54) | EGFRKCNH2IGF1RALK | |
| SCHEMBL19493296 | 0.84 | EGFR (0.70) | EGFR | |
| SCHEMBL17384828 | 0.84 | EGFR (0.70) | EGFRKCNH2 | |
| SCHEMBL19103348 | 0.83 | EGFR (0.78) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778584-A1 | PRODUCTION PROCESS OF 2-CHLORO-4-HETEROARYL-PYRIMIDINE DERIVATIVES | ARIAD Pharmaceuticals, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |