Bicarbonate

Bicarbonate

SCHEMBL2299877

CC1=CCCCC1.O=C(O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
CTSK P43235 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
ACMSD Q8TDX5 1/20 0.36
ALDH1A1 P00352 4/20 0.35
RAB9A P51151 2/20 0.35
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
GSTP1 P09211 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
FFAR1 O14842 1/20 0.33
PTPN1 P18031 1/20 0.33
HPGD P15428 2/20 0.33
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL8758237 1.00 HDAC4 (0.42) HDAC4HDAC2HDAC8HDAC6CTSK
Acetic Acid SCHEMBL28119349 0.93 HDAC4 (0.41) HDAC4HDAC2HDAC8HDAC6CTSK
Hydrogen Peroxide SCHEMBL9155269 0.93
Bicarbonate SCHEMBL9412268 0.90 HDAC4 (0.36) HDAC4HDAC2HDAC8HDAC6CTSK
Bicarbonate SCHEMBL5451359 0.90 HDAC4 (0.36) HDAC4HDAC2HDAC8HDAC6CTSK
Methyl Alcohol SCHEMBL8591271 0.87
SCHEMBL3682136 0.87 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL3959 0.87
SCHEMBL7060749 0.87 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6CTSK
SCHEMBL3297566 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10293573-B2 Micro flow channel chip and method for producing flow channel chip SUMITOMO BAKELITE COMPANY LIMITED (JP) 2019-05-21 US disclosed
US-20170354971-A1 FLOW CHANNEL DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2017-12-14 US disclosed
US-20170203537-A1 MICRO FLOW CHANNEL CHIP AND METHOD FOR PRODUCING FLOW CHANNEL CHIP SUMITOMO BAKELITE CO., LTD. (JP) 2017-07-20 US disclosed
US-9399725-B2 Temporary bonding adhesive for a semiconductor wafer and method for manufacturing a semiconductor device using the same SUMITOMO BAKELITE CO., LTD. (JP) 2016-07-26 US disclosed
US-9051452-B2 Polymer compositions for temporary bonding PROMERUS, LLC (US) 2015-06-09 US disclosed
EP-2351804-B1 USE OF A RESIN COMPOSITION AS A TEMPORARILY FIXING AGENT FOR SEMICONDUCTOR WAFER, AND PROCESS FOR PRODUCTION OF SEMICONDUCTOR DEVICE USING SAME SUMITOMO BAKELITE CO (JP) 2014-12-10 EP disclosed
US-8889524-B2 Substrate treating method, stack and semiconductor device JSR CORPORATION (JP) 2014-11-18 US disclosed
US-8633259-B2 Polymer compositions for temporary bonding PROMERUS, LLC (US) 2014-01-21 US disclosed
US-20130299946-A1 SUBSTRATE TREATING METHOD, STACK AND SEMICONDUCTOR DEVICE JSR CORPORATION (JP) 2013-11-14 US disclosed
EP-2551924-A1 METHOD OF MANUFACTURE FOR LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING ELEMENT MANUFACTURED THEREBY Sumitomo Bakelite Company Limited (JP) 2013-01-30 EP disclosed
EP-2506298-A1 PRODUCTION METHOD FOR ELECTRONIC DEVICE, ELECTRONIC DEVICE, PRODUCTION METHOD FOR ELECTRONIC DEVICE PACKAGE, AND ELECTRONIC DEVICE PACKAGE Sumitomo Bakelite Company Limited (JP) 2012-10-03 EP disclosed
US-20120228782-A1 METHOD FOR MANUFACTURING ELECTRONIC DEVICE, ELECTRONIC DEVICE, METHOD FOR MANUFACTURING ELECTRONIC DEVICE PACKAGE AND ELECTRONIC DEVICE PACKAGE Sumitomo Bakelite Co, Ltd (JP) 2012-09-13 US disclosed
WO-2012092447-A1 POLYMER COMPOSITIONS FOR TEMPORARY BONDING PROMERUS, LLC (US) 2012-07-05 WO disclosed
US-20120172479-A1 POLYMER COMPOSITIONS FOR TEMPORARY BONDING PROMERUS LLC (US) 2012-07-05 US disclosed
US-20110318938-A1 TEMPORARY BONDING ADHESIVE FOR A SEMICONDUCTOR WAFER AND METHOD FOR MANUFACTURING A SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2011-12-29 US disclosed
US-20110263095-A1 TEMPORARY BONDING ADHESIVE FOR A SEMICONDUCTOR WAFER AND METHOD FOR MANUFACTURING A SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2011-10-27 US disclosed
EP-2351804-A1 TEMPORARILY FIXING AGENT FOR SEMICONDUCTOR WAFER, AND PROCESS FOR PRODUCTION OF SEMICONDUCTOR DEVICE USING SAME Sumitomo Bakelite Company Limited (JP) 2011-08-03 EP disclosed
EP-2351805-A1 TEMPORARILY FIXING AGENT FOR SEMICONDUCTOR WAFER, AND PROCESS FOR PRODUCTION OF SEMICONDUCTOR DEVICE USING SAME Sumitomo Bakelite Company Limited (JP) 2011-08-03 EP disclosed
EP-2264112-A2 Temporary bonding adhesive for a semiconductor wafer and method for manufacturing a semiconductor device using the same, and use of a resin composition as a temporary bonding adhesive Sumitomo Bakelite Co., Ltd. (JP) 2010-12-22 EP disclosed
EP-2264113-A2 Temporary bonding adhesive for a semiconductor wafer and method for manufacturing a semiconductor device using the same, and use of a resin composition as a temporary bonding adhesive Sumitomo Bakelite Co., Ltd. (JP) 2010-12-22 EP disclosed