Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25771217 | 1.00 | DDB1 (0.46) | DDB1CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL20993884 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL19403923 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL23352419 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL23471602 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL19400507 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL14866651 | 0.80 | TP53 (0.41) | ALDH1A1MAPTL3MBTL1TP53RIPK1 | |
| SCHEMBL22731163 | 0.76 | GAA (0.47) | MAPTHTR2CTP53 | |
| SCHEMBL22727368 | 0.76 | GAA (0.47) | MAPTHTR2CTP53 | |
| SCHEMBL2329301 | 0.74 | DDB1 (0.54) | DDB1CRBNMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |