Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 20/20 | 0.73 |
| ▸ | CDK4 | P11802 | 19/20 | 0.73 |
| ▸ | CSF1R | P07333 | 16/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.73 |
| ▸ | CDK2 | P24941 | 5/20 | 0.73 |
| ▸ | CCNK | O75909 | 4/20 | 0.73 |
| ▸ | CDK9 | P50750 | 4/20 | 0.73 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.73 |
| ▸ | CDK7 | P50613 | 3/20 | 0.73 |
| ▸ | CCNH | P51946 | 3/20 | 0.73 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.73 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23010494 | 0.92 | CDK6 (0.72) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL23010875 | 0.91 | CDK4 (0.71) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL23010869 | 0.89 | CDK6 (0.77) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL23010605 | 0.89 | CDK6 (0.71) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL21267828 | 0.86 | CDK4 (0.84) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL23010873 | 0.85 | CDK6 (0.71) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL21267683 | 0.85 | CDK6 (0.89) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL21245722 | 0.84 | CSF1R (1.00) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL23010492 | 0.83 | CDK4 (0.71) | CDK6CDK4CSF1RCCNA2CDK2 | |
| SCHEMBL21267321 | 0.83 | CDK6 (0.89) | CDK6CDK4CSF1RCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030620-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-02-18 | — | — | WO | disclosed |