Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313919 | 0.79 | — | — | |
| SCHEMBL29043353 | 0.76 | KMT2A (0.84) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL23861292 | 0.76 | KMT2A (0.84) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL2301489 | 0.76 | KMT2A (0.70) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL11015380 | 0.74 | KMT2A (0.81) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6075378 | 0.72 | KMT2A (0.63) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL6152527 | 0.72 | KMT2A (0.81) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL27731718 | 0.72 | KMT2A (0.68) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL2981069 | 0.70 | KMT2A (0.61) | KMT2ANPSR1ALDH1A1KDM4ETSHR | |
| SCHEMBL9906306 | 0.70 | KMT2A (0.61) | KMT2ANPSR1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999006-B2 | Anticancer agents; mitogen-activated protein kinases (MEK) | EXELIXIS, INC. (US) | 2011-08-16 | — | — | US | claimed |