Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | KDM6B | O15054 | 2/20 | 0.60 |
| ▸ | KDM5C | P41229 | 2/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.60 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.60 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.60 |
| ▸ | KDM4A | O75164 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30614246 | 1.00 | JMJD6 (0.65) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL30171421 | 0.91 | JMJD6 (0.76) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL811785 | 0.91 | JMJD6 (0.76) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL15173427 | 0.88 | NPC1 (0.58) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL16141971 | 0.87 | JMJD6 (0.61) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL2388712 | 0.85 | NPC1 (0.58) | JMJD6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29978844 | 0.85 | NPC1 (0.58) | JMJD6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4763680 | 0.85 | JMJD6 (0.67) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL2688111 | 0.85 | JMJD6 (0.68) | JMJD6KDM4EKDM6BKDM5CKDM4C | |
| SCHEMBL1333711 | 0.85 | JMJD6 (0.68) | JMJD6KDM4EKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350311-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010056506-A1 | DIACYLGLYCEROL ACLYTRANSFERASE INHIBITORS | VIA PHARMACEUTICALS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |