Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4318032 | 0.87 | HDAC1 (0.84) | HDAC1HDAC2 | |
| SCHEMBL2212336 | 0.83 | HDAC1 (0.75) | HDAC1HDAC2 | |
| SCHEMBL2209817 | 0.83 | HDAC1 (0.80) | HDAC1HDAC2 | |
| SCHEMBL2207647 | 0.82 | HDAC1 (0.80) | HDAC1HDAC2 | |
| SCHEMBL2209766 | 0.82 | HDAC1 (0.73) | HDAC1HDAC2 | |
| SCHEMBL2209349 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2 | |
| SCHEMBL2209250 | 0.82 | HDAC1 (0.81) | HDAC1HDAC2 | |
| SCHEMBL2209626 | 0.81 | HDAC1 (0.72) | HDAC1HDAC2 | |
| SCHEMBL1066522 | 0.81 | HDAC1 (0.80) | HDAC1HDAC2 | |
| SCHEMBL2206749 | 0.81 | HDAC1 (0.83) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981874-B2 | Phosphorus derivatives as histone deacetylase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-07-19 | — | — | US | disclosed |