Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.65 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097795 | 0.87 | HCRTR2 (0.61) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL8217802 | 0.83 | HCRTR2 (0.58) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL903254 | 0.83 | HCRTR2 (0.58) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17830177 | 0.83 | HCRTR2 (0.58) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL2904344 | 0.83 | HCRTR2 (0.58) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17763483 | 0.81 | HCRTR2 (0.60) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17539260 | 0.81 | HCRTR2 (0.56) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17763480 | 0.81 | HCRTR2 (0.60) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17539230 | 0.81 | HCRTR2 (0.56) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 | |
| SCHEMBL17830170 | 0.81 | HCRTR2 (0.60) | HCRTR2HCRTR1NR1I2ADRA2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177616-B1 | NOVEL ROUTES OF SYNTHESIS FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2021-02-24 | — | — | EP | disclosed |