Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 20/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 19/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23018175 | 0.92 | HCRTR2 (0.61) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL23018177 | 0.90 | HCRTR2 (0.61) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL8217802 | 0.86 | HCRTR2 (0.58) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL17830177 | 0.86 | HCRTR2 (0.58) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL2904344 | 0.86 | HCRTR2 (0.58) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL903254 | 0.86 | HCRTR2 (0.58) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL12024777 | 0.85 | HCRTR1 (0.57) | HCRTR2HCRTR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL21612201 | 0.82 | HCRTR2 (0.54) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL8056064 | 0.79 | HCRTR1 (0.62) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL17151371 | 0.77 | HCRTR2 (0.69) | HCRTR2HCRTR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177616-B1 | NOVEL ROUTES OF SYNTHESIS FOR THE PREPARATION OF SUVOREXANT | SANDOZ AG (CH) | 2021-02-24 | — | — | EP | disclosed |