Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17085928 | 0.83 | TP53 (0.49) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL29441735 | 0.81 | TP53 (0.58) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL17085854 | 0.81 | TP53 (0.58) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL17086128 | 0.78 | TP53 (0.57) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL19984566 | 0.77 | POLB (0.52) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL30186428 | 0.76 | TP53 (0.58) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL5057271 | 0.76 | TP53 (0.58) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL23094972 | 0.75 | HPGD (0.55) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL5062829 | 0.75 | TP53 (0.57) | TP53MAPTSMN1; SMN2POLBHTT | |
| SCHEMBL4670438 | 0.73 | HPGD (0.70) | TP53MAPTSMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |